Lipid-Associated Sialic Acid (LASA) is a useful adjunct in the management of a variety of malignancies. It is best used in conjunction with other tumor markers. Elevations in blood LASA levels have been reported in patients with the following types of cancer: breast (63%), gastroenteric (65%), lung (79%), and ovarian (94%) neoplasms as well as those with leukemia (86%), lymphoma (87%), melanoma (84%), sarcoma (97%), and Hodgkin's disease (91%). Lipid-Associated Sialic Acid (LASA) levels can also be elevated in patients with certain benign diseases, including inflammatory disorders.
Preliminary studies have demonstrated that LASA concentrations are indicative of disease status in patients with leukemia, lymphoma, or cancer of the breast, ovary, or colorectum.
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